[Isolation and characteristics of monoclonal antibodies to influenza virus types A and B].
Identifieur interne : 002E07 ( Main/Exploration ); précédent : 002E06; suivant : 002E08[Isolation and characteristics of monoclonal antibodies to influenza virus types A and B].
Auteurs : T L Busse ; M L Khristova ; M V Sokolova ; I G Kharitonenkov ; M. SaranpaSource :
- Voprosy virusologii [ 0507-4088 ]
Descripteurs français
- KwdFr :
- Animaux, Anticorps monoclonaux (analyse), Anticorps monoclonaux (isolement et purification), Hybridomes (immunologie), Hémagglutinines virales (analyse), Immunisation, Immunotransfert, Rappel de vaccin, Souris, Souris de lignée BALB C, Techniques immunoenzymatiques, Virus de la grippe A (immunologie), Virus influenza B (immunologie), Électrophorèse sur gel de polyacrylamide.
- MESH :
- analyse : Anticorps monoclonaux, Hémagglutinines virales.
- immunologie : Hybridomes, Virus de la grippe A, Virus influenza B.
- isolement et purification : Anticorps monoclonaux.
- Animaux, Immunisation, Immunotransfert, Rappel de vaccin, Souris, Souris de lignée BALB C, Techniques immunoenzymatiques, Électrophorèse sur gel de polyacrylamide.
English descriptors
- KwdEn :
- Animals, Antibodies, Monoclonal (analysis), Antibodies, Monoclonal (isolation & purification), Electrophoresis, Polyacrylamide Gel, Hemagglutinins, Viral (analysis), Hybridomas (immunology), Immunization, Immunization, Secondary, Immunoblotting, Immunoenzyme Techniques, Influenza A virus (immunology), Influenza B virus (immunology), Mice, Mice, Inbred BALB C.
- MESH :
- chemical , analysis : Antibodies, Monoclonal, Hemagglutinins, Viral.
- chemical , isolation & purification : Antibodies, Monoclonal.
- immunology : Hybridomas, Influenza A virus, Influenza B virus.
- Animals, Electrophoresis, Polyacrylamide Gel, Immunization, Immunization, Secondary, Immunoblotting, Immunoenzyme Techniques, Mice, Mice, Inbred BALB C.
Abstract
Monoclonal antibodies (MCA) to influenza type A (10F) and B (5H and 6H) viruses have been prepared. By immunoblotting method, MCA 10F were found to be specific for NP-protein of influenza A virus, and MCA 5H and 6H to be specific for hemagglutinin of influenza B virus. It was established that the 10F clone interacted with all the investigated influenza A virus strains with different antigenic formulae (H1N1, H2N2, H3N2) and could be used for typing of this virus type. Clones 5H and 6H react specifically with hemagglutinins of influenza B viruses isolated in 1940, 1979, and 1983 which makes them useful for diagnosis of influenza B.
PubMed: 3064429
Affiliations:
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Le document en format XML
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Saranpa</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>1988 Sep-Oct</MedlineDate></PubDate></date><idno type="RBID">pubmed:3064429</idno><idno type="pmid">3064429</idno><idno type="wicri:Area/PubMed/Corpus">000471</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000471</idno><idno type="wicri:Area/PubMed/Curation">000471</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000471</idno><idno type="wicri:Area/PubMed/Checkpoint">000631</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000631</idno><idno type="wicri:Area/Ncbi/Merge">000F52</idno><idno type="wicri:Area/Ncbi/Curation">000F52</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F52</idno><idno type="wicri:doubleKey">0507-4088::Busse T:isolation:and:characteristics</idno><idno type="wicri:Area/Main/Merge">002F82</idno><idno type="wicri:Area/Main/Curation">002E07</idno><idno type="wicri:Area/Main/Exploration">002E07</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Isolation and characteristics of monoclonal antibodies to influenza virus types A and B].</title><author><name sortKey="Busse, T L" sort="Busse, T L" uniqKey="Busse T" first="T L" last="Busse">T L Busse</name></author><author><name sortKey="Khristova, M L" sort="Khristova, M L" uniqKey="Khristova M" first="M L" last="Khristova">M L Khristova</name></author><author><name sortKey="Sokolova, M V" sort="Sokolova, M V" uniqKey="Sokolova M" first="M V" last="Sokolova">M V Sokolova</name></author><author><name sortKey="Kharitonenkov, I G" sort="Kharitonenkov, I G" uniqKey="Kharitonenkov I" first="I G" last="Kharitonenkov">I G Kharitonenkov</name></author><author><name sortKey="Saranpa, M" sort="Saranpa, M" uniqKey="Saranpa M" first="M" last="Saranpa">M. Saranpa</name></author></analytic><series><title level="j">Voprosy virusologii</title><idno type="ISSN">0507-4088</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Monoclonal (analysis)</term><term>Antibodies, Monoclonal (isolation & purification)</term><term>Electrophoresis, Polyacrylamide Gel</term><term>Hemagglutinins, Viral (analysis)</term><term>Hybridomas (immunology)</term><term>Immunization</term><term>Immunization, Secondary</term><term>Immunoblotting</term><term>Immunoenzyme Techniques</term><term>Influenza A virus (immunology)</term><term>Influenza B virus (immunology)</term><term>Mice</term><term>Mice, Inbred BALB C</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps monoclonaux (analyse)</term><term>Anticorps monoclonaux (isolement et purification)</term><term>Hybridomes (immunologie)</term><term>Hémagglutinines virales (analyse)</term><term>Immunisation</term><term>Immunotransfert</term><term>Rappel de vaccin</term><term>Souris</term><term>Souris de lignée BALB C</term><term>Techniques immunoenzymatiques</term><term>Virus de la grippe A (immunologie)</term><term>Virus influenza B (immunologie)</term><term>Électrophorèse sur gel de polyacrylamide</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antibodies, Monoclonal</term><term>Hemagglutinins, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Antibodies, Monoclonal</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Anticorps monoclonaux</term><term>Hémagglutinines virales</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Hybridomes</term><term>Virus de la grippe A</term><term>Virus influenza B</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Hybridomas</term><term>Influenza A virus</term><term>Influenza B virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Anticorps monoclonaux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Electrophoresis, Polyacrylamide Gel</term><term>Immunization</term><term>Immunization, Secondary</term><term>Immunoblotting</term><term>Immunoenzyme Techniques</term><term>Mice</term><term>Mice, Inbred BALB C</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Immunisation</term><term>Immunotransfert</term><term>Rappel de vaccin</term><term>Souris</term><term>Souris de lignée BALB C</term><term>Techniques immunoenzymatiques</term><term>Électrophorèse sur gel de polyacrylamide</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Monoclonal antibodies (MCA) to influenza type A (10F) and B (5H and 6H) viruses have been prepared. By immunoblotting method, MCA 10F were found to be specific for NP-protein of influenza A virus, and MCA 5H and 6H to be specific for hemagglutinin of influenza B virus. It was established that the 10F clone interacted with all the investigated influenza A virus strains with different antigenic formulae (H1N1, H2N2, H3N2) and could be used for typing of this virus type. Clones 5H and 6H react specifically with hemagglutinins of influenza B viruses isolated in 1940, 1979, and 1983 which makes them useful for diagnosis of influenza B.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Busse, T L" sort="Busse, T L" uniqKey="Busse T" first="T L" last="Busse">T L Busse</name><name sortKey="Kharitonenkov, I G" sort="Kharitonenkov, I G" uniqKey="Kharitonenkov I" first="I G" last="Kharitonenkov">I G Kharitonenkov</name><name sortKey="Khristova, M L" sort="Khristova, M L" uniqKey="Khristova M" first="M L" last="Khristova">M L Khristova</name><name sortKey="Saranpa, M" sort="Saranpa, M" uniqKey="Saranpa M" first="M" last="Saranpa">M. Saranpa</name><name sortKey="Sokolova, M V" sort="Sokolova, M V" uniqKey="Sokolova M" first="M V" last="Sokolova">M V Sokolova</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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